Which symptoms could indicate digoxin toxicity?

• A. Headache and rash.
• B. Nausea, vomiting, vision changes, or arrhythmias.
• C. Abdominal bloating only.
• D. Dizziness unrelated to GI symptoms.

Answer: (B)

Digoxin toxicity most reliably presents with a cluster of effects on the gut, the eyes, and the heart. Nausea and vomiting are common early signs, reflecting irritation from excess digoxin. Visual changes—such as blurred vision or seeing yellow halos—are classic and occur due to digoxin’s CNS and retinal effects. Arrhythmias arise because too much digoxin alters cardiac conduction, often through increased vagal tone and disturbed AV node function, which can lead to dangerous rhythms. So the combination of GI symptoms, visual disturbances, and rhythm problems points most clearly to toxicity. Headache and rash aren’t typical features of digoxin toxicity; abdominal bloating by itself is nonspecific, and dizziness without accompanying GI or visual symptoms doesn’t strongly indicate toxicity. If this is suspected, verify the digoxin level and assess electrolytes and kidney function.